Sleep disorders, insomnia
2015年8月15日土曜日
Supplements of insomnia measures associated with bipolar disorder
Specialized journal (electronic version) of the month of spiritual science, Review to verify the herbal supplements for anxiety and insomnia associated with bipolar disorder had been reported.
(Aust N Z J Psychiatry. 2014 Jun 19)
In bipolar disorder, it may show symptoms such as anxiety and insomnia among of the total state and depression,
Also used supplements as self-medication.
In this review,
The effectiveness of the supplements for anxiety and insomnia associated with bipolar disorder were examined.
In particular,
Against anxiety and insomnia in bipolar disorder,
Case reports, open-label study, herbal supplement that has been shown by the placebo-controlled trials have been verified.
In human clinical research
11 kinds of herbal supplements is subject,
result of the mechanism of action, efficacy, side effects, such as the interaction has been analyzed,
In the current state of the evidence, valerian is the insomnia and the most useful anxiety associated with bipolar disorder, it is considered that.
In addition, only herbal supplements In this review will have been the subject.
In addition to herbs, the validity of the bipolar disorder by omega-3 fatty acids (EPA and DHA) have been known.
In DHC, and covers the related supplement / health food.
Valerian
Complex supplement "relaxed"
EPA
DHA
The sleep-improving effect by zinc
Where it had examined the effects of zinc to sleep, clinical studies showed insomnia improvement effect of long-term administration of zinc-melatonin, magnesium, it had been reported from the Italian group (University of Pavia).
(J Am Geriatr Soc 2011 Jan; 59 (1):. 82-90.)
Currently, an increase in sleep disorders, insomnia in Japan has become a problem.
Sleep disorders, in order to be related to the risk of a variety of lifestyle-related diseases, the treatment will be determined to be appropriate diagnosis.
Sleep onset disorder also observed to be elderly to young people,
In the elderly will continue to increase in mid-arousal.
On the other hand, insufficient intake of zinc, it is shown in the diet study of Japanese, it has been known as the cause of such taste failure.
Well, in this study,
Zinc for primary insomnia, magnesium, works by melatonin administration has been verified.
In particular,
As a random, double-blind, placebo-controlled trial,
43 people of Italy of long-term care facilities (mean age 78.3 years) to the subject,
- Supplementation group (22 people),
(5 mg melatonin, 225 mg magnesium, ingested one hour before bedtime 11.25 mg zinc)
- Placebo group 21 people
For two groups,
8-week intervention study was conducted.
The main outcomes,
It is a sleep-related index (PSQI),
As a sub-outcome,
Epworth Sleepiness Scale, the Leeds Sleep Evaluation Questionnaire (LSEQ), the Short Insomnia Questionnaire (SDQ), SF-36 was used.
In addition, in wearable equipment, sleep time has been measured.
As a result of the analysis,
Supplementation group, compared to the placebo group, PSQI had been significantly improved.
(P <.001)
Also,
In LSEQ, in all four regions, significant improvement was observed.
(Ease of getting to sleep, P <.001; quality of sleep, P <.001; hangover on awakening from sleep, P = .005; alertness and behavioral integrity the following morning, P = .001).
Other,
SDQ score (P <.001), sleep time (P <.001), has the action of the SF-36 physical score (P = .006) even supplementation group was observed.
From the above data,
Against primary insomnia in residents of long-term care facility,
Zinc, magnesium, the effect of melatonin is suggested.
Insufficient intake of zinc, it believed that can also be a cause of sleep disorders.
In the National Health and Nutrition Examination Survey, and inadequate intake of zinc is shown,
Ingestion of zinc supplements are recommended.
Further, among the carotenoids, astaxanthin, has a chelating action of zinc and promotes the absorption of zinc by combination with zinc.
(Astaxanthin itself is, in the normal intake, not observed effects on sleep. Can be administered in large quantities to the animal, but there is basic research that has improved sleep.)
In DHC, as the related supplements, we are dealing with the following products.
Zinc
Multi-mineral
Astaxanthin
Valerian
Loose
Theanine
Stress reduction and sleep improvement action by ornithine
Professional journal of nutrition, L- anti-stress effect of the clinical studies showed sleep improving action ornithine, Kirin Co., had been reported from Ltd. group.
(Nutr J. 2014 Jun 3; 13: 53.)
L- ornithine is a kind of functional amino acid, is widely used as a supplement to the physical fatigue of chronic.
In this study,
Effects on stress and sleep with L- ornithine has been verified.
In particular,
As a random, double-blind, placebo-controlled trial,
I'm feeling a mild stress and fatigue,
Intended for healthy people 42 people of Japanese,
L- ornithine (400 mg / day) or placebo has been administered for 8 weeks.
As an evaluation index,
Blood cortisol, DHEA-S values,
POMS for mood and sleep, AIS (Athens insomnia scale), OSA-MA was used.
As a result of the analysis,
As compared to the placebo group,
In L- ornithine administration group,
Blood cortisol values and cortisol / DHEA-S is significantly reduced,
The effect of improving the quality of sleep was also observed.
From the above data,
Stress-reducing action and sleep improving action by L- ornithine supplements are suggested.
In DHC,
It is the product of the L- ornithine-containing supplements.
Ornithine 30 days
Clean from morning clam power! Also to the combustion support! Also to accompany sake!
The sleep disorder improving action by the milk protein hydrolyzate (Rakutiumu)
Professional journal of sleep research, clinical research had been reported that showed the sleep disorder improving action by the milk protein hydrolyzate (Rakutiumu).
(Open Sleep Journal 2009; 2:. 26-32)
Currently, many of the Japanese, there is dissatisfaction in sleep,
Not many cases of sleep disorders, insomnia.
To sleep disorders, (type not falling asleep quite) sleep onset disorder and, mid-arousal (type that would occur in the middle) and so on.
For sleep disorders,
In the medical institutions are prescription sleep-inducing agent, but might be a bit high hurdle.
You can self-care in general for drugs and supplements.
Among the supplements, the herb, you valerian is used.
In addition,
Peptide (milk protein hydrolyzate) derived from casein, which is the main component of milk proteins contained in the milk,
Relaxation and insomnia improvement has been found,
It is used as a functional food ingredient.
Is a functional food ingredients derived from casein tryptic hydrolyzate of milk protein Rakutiumu (Lactium) is,
And functionality display was observed in other countries,
For example, in France,
"Tension response to stress can be relaxed."
You can display such.
(Rakutiumu is Ingredia SA company functional materials of milk protein manufacturers dairy union of France became the mother.)
(Even adults to ingest milk, in adults of enzyme system, the bioactive peptides have been and can not get enough.)
Well, in this study,
Impact of sleep disorders due to milk protein hydrolyzate (Rakutiumu) has been verified.
Specifically,
Japanese 32 people with sleep disorders (25 to 40 years) to the subject,
Casein tryptic hydrolyzate (Rakutiumu, 150mg) dose group (20 people)
Placebo group (12 people) were administered four weeks,
Comparison of sleep-related indicators have been made.
As a result of the analysis,
PSQI is that significant improvement of the total score in (Pittsburgh sleep questionnaire) was observed.
In particular, reduction of the reduction of sleep latency failure in (improvement) and the day (sleepiness) (improvement) is remarkable, improvement of quality of sleep has been suggested.
In addition, adverse events of particular problem not been found.
From the above data,
Insomnia improvement action by the casein tryptic hydrolyzate (Rakutiumu) has been suggested.
In DHC,
Rakutiumu containing complex supplements; also I have done studies using (Gusuka ® Rakutiumu 150mg + Kuwansou concentrated extract powder 300㎎ + ornithine hydrochloride 400mg + arginine 600mg).
Specifically,
To target the Japanese to sue the sleep disorders,
It was administered two weeks,
PSQI (Pittsburgh sleep questionnaire) improvement of the score,
OSA sleep questionnaire MA version improved,
Improvement by action meter trend has been found.
In DHC, as a functional food to improve the quality of insomnia measures and sleep, we are dealing with the following products.
Valerian 30 days
Su~u and soundly, the next morning bright neat! Supports daily restful mood
Loose
A pleasant night time to you. 7 efficiently approach component to peacefully
Gusuka 30 encased
Comfortable rest and the exhilarating morning. To support a comfortable rhythm
Sleep disorders in children by smartphone
Professional journal of the month of pediatrics (electronic version), studies that examined the impact of sleep in children with TV and smartphones, has been reported from the US group (University of California Berkeley).
(Pediatrics. 2015 Jan 5)
TV and smartphones, such as various environmental, affects the sleep of children.
Conventional, and watch TV, but has been known to sleep shortening of children, in recent years, the influence of the digital equipment of the small screen such as smartphones are concerned.
(Is emitted from the screen of these portable electronic terminal, short-wavelength light, the blue light, has been suggested that an adverse effect on the harm real rhythm.)
In this study,
The influence of the children to sleep by the television and smartphones have been verified.
Specifically,
As a cross-sectional study,
From 2012 through 2013,
To target the fourth grade and 2,048 people of seventh grade of Massachusetts, USA,
And the environment with TV and smartphones, has been examined association with sleep.
(It is part of the research on childhood obesity that Massachusetts Childhood Obesity Research Demonstration Study.)
As a result of the analysis,
Bedtime to,
In children it has placed a small screen devices such as smart phones in the vicinity,
Otherwise, compared to children not,
Sleep time per day, 20.6 minutes, was found to be significantly shorter.
(95% CI, -29.7 to -11.4)
In addition,
the proportion of children rest is insufficient, or sleep feels that insufficient was also found to be 39% higher.
(1.39; 95% CI, 1.21 to 1.60)
on the other hand,
Children there is a TV in the room,
Compared to children with no TV,
Sleep time is 18.0 minutes, but has been a significantly shorter,
(95% CI, -27.9 to -8.1)
The proportion of rest and sleep to feel inadequate, significant differences not been found.
However,
Indeed, I have been watching TV or DVD, or if it were using a video game computer games,
Sleep outcomes and significantly correlated, that is, had been correlated with the percentage that feel the lack of sleep.
(P <.01)
From the above data,
As the cause of children with sleep disorders (reduction in the quality of the shortening and sleep sleep time),
That there is a small screen devices and mobile terminal devices such as smart phones at bedtime,
Sleeping in a room with a TV,
To or utilized or watch them at bedtime,
That it will be considered.
The improvement of sleep disorders, insomnia in children, measures such as bedtime smartphone usage restrictions it will be considered useful.
Failure of the eye by blue light has become a problem.
Component to suppress the failure of the eye due to functional food ingredients in the blue light,
There is lutein.
Lutein, other contained in plant foods such as spinach and corn, also available as a supplement.
For the prevention and risk reduction of age-related macular degeneration (AMD), it has lutein supplements recommended widely accepted.
In a recent study,
The macular pigment density by lutein (MPOD) increasing effect: meta-analysis
The visual processing speed improvement effect of lutein
There are also reports that.
In DHC, as a functional food to improve the quality of insomnia measures and sleep, we are dealing with the following products.
Valerian 30 days
Su~u and soundly, the next morning bright neat! Supports daily restful mood
Loose
A pleasant night time to you. 7 efficiently approach component to peacefully
Gusuka 30 encased
Comfortable rest and the exhilarating morning. To support a comfortable rhythm
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